Lab focus
The goal of my lab is to study how deficits in brain development affect cognitive function. We start from the identification of genes which cause neurodevelopmental diseases such as intellectual disability, autism spectrum disorder or brain malformations, and then use animal models (mouse and zebrafish) to recapitulate the human disease, understand pathogenesis and study the molecular mechanisms of development. We are particularly interested in intracellular signaling deficits that could be targeted for the development of novel therapies.
Latest lab news
9/1/21 - Abby Heller and Brian Gural have left the lab to start their graduate studies at Rutgers and UNC, respectively! Kyle Flannery (Biomedical Sciences Program) has joined the lab as a new PhD student.
2/1/21 - Aniket Bhattacharya has joined the lab as a postdoctoral fellow to study sex-specific mechanisms of neurodevelopmental disorders.
12/10/20 - Pablo Munoz Llancao has taken a new position in the Ferguson lab at Yale School of Medicine.
10/16/20 - Paola Parlanti is going back to Italy taking a new position at the Italian Institute of Technology. Safe travels, Paola!
9/16/20 - A study on the identification of novel mutations in LAMA2 using exome sequencing and CNV analysis was just published on Molecular Genetics & Genomic Medicine (here)! Lots of writing went on during the shut-down!!
9/1/20 - Luka Turkalj (Graduate Program in Neuroscience) has officially joined the lab to start his doctoral work on the mechanisms controlling sex-specific signaling in the typical and autistic brain.
7/1/20 - Brittany Karas has joined the lab as a postdoctoral fellow to study zebrafish models of congenital muscular dystrophy.
6/30/20 - Adele Mossa has taken a new position as a fellow in the laboratory of Silvia DeRubeis at Mount Sinai.
6/22/20 - Back to work! Staying as safe as we can. Distance and wear your masks!! Also new collaborative study is online today on novel variants in MFSD2A in congenital microcephaly syndrome (here).
5/28/20 - A collaborative study on uridine treatment in CAD mutations is out in Genetics in Medicine (here)!
5/3/20 - Our latest work in collaboration with Marina Mora's group in Milan showing on loss of function mutations in TBCK leading to myopathic changes and encephalopathy is out in Muscle and Nerve (here).
3/16/20 - The lab is closed for the Covid-19 epidemic! Stay safe out there.
12/23/19 - Adele Mossa and Chiara just published a review article summarizing sex-specific deficits in animal models of neurodevelopmental disorders in the Journal of Neuroscience Research (here). It's open access for everyone to read!
Read more news and see lab events
9/1/21 - Abby Heller and Brian Gural have left the lab to start their graduate studies at Rutgers and UNC, respectively! Kyle Flannery (Biomedical Sciences Program) has joined the lab as a new PhD student.
2/1/21 - Aniket Bhattacharya has joined the lab as a postdoctoral fellow to study sex-specific mechanisms of neurodevelopmental disorders.
12/10/20 - Pablo Munoz Llancao has taken a new position in the Ferguson lab at Yale School of Medicine.
10/16/20 - Paola Parlanti is going back to Italy taking a new position at the Italian Institute of Technology. Safe travels, Paola!
9/16/20 - A study on the identification of novel mutations in LAMA2 using exome sequencing and CNV analysis was just published on Molecular Genetics & Genomic Medicine (here)! Lots of writing went on during the shut-down!!
9/1/20 - Luka Turkalj (Graduate Program in Neuroscience) has officially joined the lab to start his doctoral work on the mechanisms controlling sex-specific signaling in the typical and autistic brain.
7/1/20 - Brittany Karas has joined the lab as a postdoctoral fellow to study zebrafish models of congenital muscular dystrophy.
6/30/20 - Adele Mossa has taken a new position as a fellow in the laboratory of Silvia DeRubeis at Mount Sinai.
6/22/20 - Back to work! Staying as safe as we can. Distance and wear your masks!! Also new collaborative study is online today on novel variants in MFSD2A in congenital microcephaly syndrome (here).
5/28/20 - A collaborative study on uridine treatment in CAD mutations is out in Genetics in Medicine (here)!
5/3/20 - Our latest work in collaboration with Marina Mora's group in Milan showing on loss of function mutations in TBCK leading to myopathic changes and encephalopathy is out in Muscle and Nerve (here).
3/16/20 - The lab is closed for the Covid-19 epidemic! Stay safe out there.
12/23/19 - Adele Mossa and Chiara just published a review article summarizing sex-specific deficits in animal models of neurodevelopmental disorders in the Journal of Neuroscience Research (here). It's open access for everyone to read!
Read more news and see lab events